It will run it, but the timing table in the firmware may not be ideal. Mostly, the computer affects ignition timing. Under closed loop steady state conditions, the fueling will be determined by O2 sensor feedback crosscounts and is not as much affected by engine size. With that said, you may need to use different primary rods to deliver enough fuel for a given duty cycle of the MCS (mixture control solenoid) in the carb. The timing table, however, is a fixed table that may be too little or too much under certain load/rpm conditions. Give it a try. That cam and compression may be just right for the timing already programmed in the ECM. You always have the option of getting a non-computer Q-Jet and standard HEI distributor if there are issues..
This is what im installing..
My 403 build
.030” over bore with cast pistons
Crank was turned .010” rods and mains
Rods were resized and ARP rod bolts were installed
The crank and rotating assembly (crank, harmonic balancer & flywheel balanced together) were balanced
The block was line honed
Block was decked .20”
Melling oil pump, standard flow & pressure
Howard’s roller cam (you’ve seen the cam card)
Heads were fitted with the larger 2.00/1.6 valves and light bowl work
Heads had the exhaust cross overs filled as we’ve discussed, as well as the port dividers welded then resurfaced
Heads were milled (67cc chambers after it was all said and done)
Comp Cams valve springs, retainers and locks
Comp roller tip rockers and guide plates
Hardened pushrods (I think they’re Summit Racing)
Cloyes double roller timing set
Cam was degreed at 0° or straight up
Edelbrock RPM intake
Street Avenger 670 carb
New HEI distributor with brass gear (for the roller cam)
9.5 to 1 compression ratio